Alcohol da cortisol
 Alcohol da cortisol |
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Barasa da cortisol suna da dangantaka mai rikitarwa. Yayin da cortisol shine hormone damuwa, shan barasa na iya haifar da ƙara yawan matakan cortisol a cikin jiki a kan lokaci. Wannan na iya zama matsala saboda cortisol na iya rufe wasu ayyukan jiki na ɗan lokaci, mai yuwuwar haifar da lalacewa ta jiki.
Cortisol
[gyara sashe | gyara masomin]Cortisol shine hormone damuwa wanda glandon adrenal ya ɓoye, wanda ya zama wani ɓangare na axis hypothalamic-pituitary-adrenal (HPA) . Yawancin lokaci ana fitar da shi a lokutan babban damuwa da aka tsara don taimakawa mutum ya jimre da yanayi mai damuwa. [1] Sakamakon cortisol yana haifar da ƙara yawan ƙwayar zuciya da hawan jini da kuma rufewar wucin gadi na tafiyar matakai na rayuwa kamar narkewa, haifuwa, girma, da rigakafi a matsayin hanyar adana makamashi don amsa damuwa. Sakin cortisol na yau da kullun na tsawon lokaci wanda babban damuwa na dogon lokaci ya haifar zai iya haifar da:
- Gajiya
- Hawan jini
- Ucers
- Ci gaban da ya hana
- Ciwon daji
- Haɗawar jijiyoyi a lokacin tsufa
- Rashin tsarin rigakafi. [2]
Barasa da cortisol hulɗa
[gyara sashe | gyara masomin]Babban matakan cortisol an danganta su da yawan shan barasa, wanda wataƙila saboda rashin tsari (rauni na hana hanawa) na axis na HPA. [3]
Tarihi
[gyara sashe | gyara masomin]Bincike kan tasirin barasa akan cortisol ya samo asali ne tun shekarun 1950. Yawancin bincike sun nuna alaƙa tsakanin su biyun; duk da haka, an iyakance su ga shan barasa na ɗan lokaci. Nazarin ɗan adam na farko don tantance tasirin barasa na dogon lokaci akan cortisol an gudanar da shi a cikin 1966 (Mendelson et al.). Sun sami matakan cortisol masu ƙarfi a cikin masu shan giya da waɗanda ba sa maye yayin shan giya. Cortisol gabaɗaya ya kasance mafi girma a cikin barasa fiye da waɗanda ba sa maye, yana nuna cewa barasa yana da tasiri na dogon lokaci akan tsarin endocrine. Har ila yau, masu shan giya suna da matakan cortisol mafi girma bayan an dakatar da shan giya, suna nuna alamun janyewa (alamar hormonal na barasa). [4]
Abubuwan da aka gano na baya-bayan nan
[gyara sashe | gyara masomin]Binciken kwanan nan yana goyan bayan wannan ƙaƙƙarfan haɗin gwiwa tsakanin yawan amfani da barasa da haɓaka matakan cortisol. A cikin binciken daya, an dauki matakan cortisol na fitsari na dare daga mutanen da suke shan barasa akai-akai tare da ƙaramin adadin barasa. Mutanen da suka sha fiye da barasa suna da matakan cortisol mafi girma da ƙananan sauye-sauye na zuciya (wanda tsarin kulawa mai zaman kansa, ANS ke sarrafawa), yana ba da shawara tsakanin haɗin HPA da ANS. Mutanen da suka fi shan barasa suna da hawan jini da wahalar barci, wanda ke nuni da girman matakan cortisol. [5]
Fasaha ta baya-bayan nan ta baiwa masu bincike damar auna matakan cortisol a cikin gashin ɗan adam (yana nuna tarin cortisol a cikin dogon lokaci). An yi amfani da wannan hanyar aunawa don kwatanta matakan cortisol na dogon lokaci a cikin barasa, masu shaye-shaye, da masu shan giya. Ɗaya daga cikin binciken da aka yi kwanan nan ya nuna cewa masu shan barasa suna da matakan cortisol na gashi sau uku zuwa hudu fiye da masu shan giya ko masu shan giya (daidai da binciken da ya gabata wanda ke nuna lokutan shan barasa yana da alaƙa da haɓakar matakan cortisol). Masu shaye-shaye da masu shan giya suna da ƙananan matakan cortisol iri ɗaya, wanda ke nuna cewa matakan cortisol a ƙarshe sun dawo daidai bayan tsawaitawa. [6]
Manazarta
[gyara sashe | gyara masomin]- ↑ Dai, Xing; Thavundayil, Joseph; Santella, Sandra; Gianoulakis, Christina (2007). "Response of the HPA-axis to alcohol and stress as a function of alcohol dependence and family history of alcoholism". Psychoneuroendocrinology. 32 (3): 293–305. doi:10.1016/j.psyneuen.2007.01.004. PMID 17349749. S2CID 39315868.
- ↑ Lupien, Sonia J.; McEwen, Bruce S.; Gunnar, Megan R.; Heim, Christine (2009). "Effects of stress throughout the lifespan on the brain, behaviour and cognition". Nature Reviews Neuroscience. 10 (6): 434–45. doi:10.1038/nrn2639. PMID 19401723. S2CID 205504945.
- ↑ Dai, Xing; Thavundayil, Joseph; Santella, Sandra; Gianoulakis, Christina (2007). "Response of the HPA-axis to alcohol and stress as a function of alcohol dependence and family history of alcoholism". Psychoneuroendocrinology. 32 (3): 293–305. doi:10.1016/j.psyneuen.2007.01.004. PMID 17349749. S2CID 39315868.
- ↑ Mendelson, Jack; Stein, Stefan (1966). "Serum Cortisol Levels in Alcoholic and Nonalcoholic Subjects During Experimentally Induced Ethanol Intoxication". Psychosomatic Medicine. 28 (4): 616–26. CiteSeerX 10.1.1.503.1374. doi:10.1097/00006842-196607000-00037. S2CID 147372625. Retrieved 2014-01-07.
- ↑ Thayer, Julian F.; Hall, Martica; Sollers, John J.; Fischer, Joachim E. (2006). "Alcohol use, urinary cortisol, and heart rate variability in apparently healthy men: Evidence for impaired inhibitory control of the HPA axis in heavy drinkers". International Journal of Psychophysiology. 59 (3): 244–50. doi:10.1016/j.ijpsycho.2005.10.013. PMID 16325293.
- ↑ Stalder, Tobias; Kirschbaum, Clemens; Heinze, Kareen; Steudte, Susann; Foley, Paul; Tietze, Antje; Dettenborn, Lucia (2010). "Use of hair cortisol analysis to detect hypercortisolism during active drinking phases in alcohol-dependent individuals". Biological Psychology. 85 (3): 357–60. doi:10.1016/j.biopsycho.2010.08.005. PMID 20727937. S2CID 14554271.