Anne O'Garra
 Anne O'Garra | |
|---|---|
.jpg) | |
| Rayuwa | |
| Haihuwa | 1954 (71/72 shekaru) |
| ƙasa | Birtaniya |
| Karatu | |
| Harsuna | Turanci |
| Sana'a | |
| Sana'a |
immunologist (en)  da likita |
| Employers |
Francis Crick Institute (en) |
| Kyaututtuka | |
| Mamba |
European Molecular Biology Organization (mul) The Royal Society (mul) National Academy of Sciences (en) |
| www3.imperial.ac.uk… da crick.ac.uk… | |
Anne O'Garra (an haife ta a shekara ta 1954) [1] Masanin rigakafi Burtaniya ce wacce ta yi muhimman abubuwan da ta gano game da tsarin aikin Interleukin 10.[2][3]
Tarihin rayuwa
[gyara sashe | gyara masomin]An haife ta ne a Gibraltar ga Louis O'Garra da Theresa O'Garr a shekara ta 1954. [ana buƙatar ƙa'ida][ana buƙatar hujja][<span title="This claim needs references to reliable sources. (March 2025)">citation needed</span>]
A Cibiyar Nazarin Kiwon Lafiya ta Kasa (NIMR), ta sami Ph.D. a cikin ilimin microbiology, ta zauna a can don shekaru hudu Bayan digiri a cikin rigakafi.
A shekara ta 1987, O'Garra ta bar Ingila zuwa Palo Alto, California, don yin aiki a Cibiyar Nazarin DNAX, inda ta zama babban ma'aikaciyar masanin kimiyya a sashen immunobiology.[4] A shekara ta 2001, ta zama shugabar Sashen Immunoregulation a Majalisar Binciken Kiwon Lafiya NIMR a London.[5] Tun daga shekara ta 2015, ta kasance mataimakiyar darektan bincike da kuma jagoran kungiyar a Cibiyar Francis Crick, cibiyar da ta maye gurbin NIMR.
Bincike
[gyara sashe | gyara masomin]An san O'Garra da gudummawar da ta bayar wajen fahimtar cibiyar sadarwa mai rikitarwa na sel-cell da kuma hulɗar cytokine da ke tsara shigarwa da kuma murkushewar martani na rigakafin sel. Ita ce ta farko da ta gano ayyukan rigakafi na Interleukin-10 (IL-10), wanda ke hana gabatarwar antigen ta sel dendritic da macrophages kuma yana rage samar da cytokines na proinflammatory. Ta kuma gano cewa Kwayoyin dendritic suna samar da interleukin mai mahimmanci don kunna T-cell (IL-12) da kuma kawar da cututtukan intracellular kuma IL-10 yana sarrafa wannan samarwa.[1]
Kyaututtuka da girmamawa
[gyara sashe | gyara masomin]Ita 'yar'uwa ce ta Royal Society, Ƙungiyar Amurka don Ci gaban Kimiyya da Kwalejin Kimiyya ta Kiwon Lafiya . Ita memba ce mai daraja ta British Society for Immunology . [6] A cikin 2020, Ƙungiyar Cytokine da Interferon ta Duniya ta ba da lambar yabo ta Membership Award ga O'Garra saboda gudummawar da ta bayar a fagen. [7]
Manazarta
[gyara sashe | gyara masomin]- ↑ O'Garra, A. (24 December 2012). "Driving change in tuberculosis research: an interview with Anne O'Garra". Disease Models & Mechanisms. 6 (1): 6–8. doi:10.1242/dmm.011429. PMC 3529333. PMID 23268534.
- ↑ "Anne O'Garra Profile" (PDF). Archived from the original (PDF) on 2012-02-16. Retrieved 2008-07-24.
- ↑ Moore, Kevin W.; de Waal Malefyt, Rene; Coffman, Robert L.; O'Garra, Anne (2001). "Interleukin-10And Theinterleukin-10 Receptor". Annual Review of Immunology. 19 (1): 683–765. doi:10.1146/annurev.immunol.19.1.683. ISSN 0732-0582. PMID 11244051.
- ↑ "ScienceWatch".
- ↑ "National Institute for Medical Research". Archived from the original on September 17, 2009. Retrieved July 19, 2010.
- ↑ "Honorary members | British Society for Immunology".
- ↑ "ICIS 2020 Honorary Lifetime Membership Award bestowed on Anne O'Garra". International Cytokine & Interferon Society (in Turanci). 2020-10-20. Retrieved 2020-10-24.