Dopamine
 Dopamine | |
|---|---|
type of chemical entity (en)  | |
| Bayanai | |
| Ƙaramin ɓangare na |
catecholamine (en) da phenethylamine alkaloid (en) |
| Amfani | magani |
| Stylized name (en) | DOPamine |
| Sinadaran dabara | C₈H₁₁NO₂ |
| Canonical SMILES (en) | C1=CC(=C(C=C1CCN)O)O |
| Medical condition treated (en) |
kidney disease (en) , bradycardia (en) da neurogenic shock (en) |
| Contributing factor of (en) |
decision making (en) |
| Significant drug interaction (en) |
phenelzine (en) , linezolid (en) , phenelzine (en) , phenelzine (en) da phenelzine (en) |
| Manufacturer (en) |
Pfizer (mul) |
| Produced by (en) |
Dopaminergic cell groups (en) |
Dopamine, wanda ake siyarwa a ƙarƙashin sunan Intropin da sauransu, magani ne da aka fi amfani da shi wajen magance matsin jini, jinkirin bugun zuciya wanda ke haifar da alamomi, kuma, idan ba a samun epinephrine ba, dakatarwar zuciya.[1] A cikin jarirai da aka haifa ya ci gaba da zama magani da aka fi so don ƙarancin hawan jini.[2] A cikin yara ana fi son epinephrine ko norepinephrine yayin da a cikin manya ana fi son norepinefrine don ƙananan hawan jini.[3][4] Ana ba da shi ta hanyar jijiyan jini ko intraosseously a matsayin ci gaba da ruwa.[1] Tasirin yawanci yakan fara ne a cikin minti biyar.[1] Ana ƙara yawan su don yin tasiri.[1]
Sakamakon cututtuka na yau da kullun sun haɗa da kara aikin koda, bugun zuciya mara kyau, ciwon kirji, amai, ciwon kai, ko damuwa.[1] Idan ya shiga cikin nama mai laushi a kusa da jijiya gida mutuwa na iya faruwa.[1] Ana iya ba da maganin phentolamine don ƙoƙarin rage wannan haɗarin.[1] Ba a san ko dopamine yana da aminci don amfani da shi a lokacin daukar ciki ko shayarwa ba.[1] A ƙananan allurai dopamine galibi yana haifar da Masu karɓar dopamine da masu karɓa na β1-adrenergic yayin da a manyan allurai yana aiki ta hanyar Masu karɓar α-adrenergic.[1]
An fara hada Dopamine a cikin dakin gwaje-gwaje a cikin 1910 ta hanyar George Barger da James Ewens a Ingila.[5] Yana cikin Jerin Magunguna Masu Muhimmanci na Hukumar Lafiya ta Duniya.[6] Kudin da aka kashe a kasashe masu tasowa na akwati na 400mg yana tsakanin $ 0.28 da $ 0.60 (USD) tun daga shekarar 2014.[7] A cikin ilimin lissafin ɗan adam Neurotransmitter)" id="mwcw" rel="mw:WikiLink" title="Dopamine (neurotransmitter)">dopamine ne neurotransmitter da kuma hormone.
Bayanan da aka ambata
[gyara sashe | gyara masomin]- 1 2 3 4 5 6 7 8 9 "Dopamine Hydrochloride". drugs.com. American Society of Health-System Pharmacists. June 29, 2016. Archived from the original on 14 September 2016. Retrieved 15 July 2016.
- ↑ Bhayat, SI; Gowda, HM; Eisenhut, M (8 May 2016). "Should dopamine be the first line inotrope in the treatment of neonatal hypotension? Review of the evidence". World Journal of Clinical Pediatrics. 5 (2): 212–22. doi:10.5409/wjcp.v5.i2.212. PMC 4857235. PMID 27170932.
- ↑ De Backer, D; Aldecoa, C; Njimi, H; Vincent, JL (March 2012). "Dopamine versus norepinephrine in the treatment of septic shock: a meta-analysis*". Critical Care Medicine. 40 (3): 725–30. doi:10.1097/ccm.0b013e31823778ee. PMID 22036860.
- ↑ Dellinger, RP; Levy, MM; Rhodes, A; Annane, D; Gerlach, H; Opal, SM; Sevransky, JE; Sprung, CL; Douglas, IS; Jaeschke, R; Osborn, TM; Nunnally, ME; Townsend, SR; Reinhart, K; Kleinpell, RM (February 2013). "Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012". Critical Care Medicine. 41 (2): 580–637. doi:10.1097/CCM.0b013e31827e83af. PMID 23353941.
- ↑ Fahn S (2008). "The history of dopamine and levodopa in the treatment of Parkinson's disease". Movement Disorders. 23 Suppl 3: S497–508. doi:10.1002/mds.22028. PMID 18781671.
According to Hornykiewicz,6 dopamine was first synthesized by George Barger and James Ewens in 1910 at the Wellcome labs in London, England.
- ↑ Empty citation (help)
- ↑ "Dopamine". International Drug Price Indicator Guide. Archived from the original on 22 January 2018. Retrieved 5 December 2015.