Hydralazine
 Hydralazine | |
|---|---|
type of chemical entity (en)  | |
| Bayanai | |
| Ƙaramin ɓangare na |
alkaloid (en) |
| Amfani | magani |
| Stylized name (en) | hydrALAZINE |
| Sinadaran dabara | C₈H₈N₄ |
| Canonical SMILES (en) | C1=CC=C2C(=C1)C=NN=C2NN |
| World Health Organisation international non-proprietary name (en) | hydralazine |
| Found in taxon (en) |
Achillea pseudopectinata (mul) , Achillea odorata (mul) da Achillea depressa (mul) |
| Medical condition treated (en) |
pulmonary hypertension (en) , malignant hypertension (en) , congestive heart failure (en) , Hawan jini da Hawan jini |
| Pregnancy category (en) |
Australian pregnancy category C (en) da US pregnancy category C (en) |
| LiverTox likelihood score (en) |
LiverTox toxicity likelihood category A (en) |
| Subject has role (en) |
antihypertensive drug (en) , vasodilator agent (en) da WHO essential medicine (en) |
Hydralazine, wanda ake siyarwa a ƙarƙashin sunan alama Apresoline da sauransu, magani ne da ake amfani da shi don magance hawan jini da gazawar zuciya.[1] Wannan ya haɗa da hawan jini mai yawa a cikin ciki da hawan jinin da ke haifar da alamomi.[2] An gano yana da amfani sosai a cikin gazawar zuciya, tare da isosorbide dinitrate, don maganin mutanen da suka fito daga Afirka.[1] Ana ba da shi ta baki ko ta hanyar allura a cikin jijiya.[2] Tasirin yawanci yakan fara ne a kusa da minti sha biyar (15) kuma ya kai sa'o'i shida.[1]
Sakamakon cututtuka na yau da kullun sun haɗa da ciwon kai da bugun zuciya mai sauri.[1] Ba kullun ba amma mummunan sakamako sun haɗa da cututtukan jijiyoyi da zazzabin miyagun ƙwayoyi.[3] Ba a ba da shawarar ga mutanen da ke fama da Cutar jijiyoyin zuciya ko kuma wadanda ke fama da cututtukan zuciya na rheumatic wanda ke shafar bawul din mitral.[1] A cikin wuce gona da iri, cutar lupus-like na iya faruwa.[3] A cikin waɗanda ke fama da Cutar koda ana ba da shawarar ƙananan sashi.[2] Hydralazine yana cikin dangin vasodilator na magunguna kuma yana aiki ta hanyar haifar da fadada jijiyoyin jini.[3]
An gano Hydralazine yayin da masana kimiyya a Ciba ke neman magani don zazzabin cizon sauro.[4] An ba da izini a cikin 1949. Yana cikin Jerin Magunguna Masu Muhimmanci na Hukumar Lafiya ta Duniya.[5] Kudin da aka kashe a kasashe masu tasowa kusan US $ 2.78-9.11 ne a kowane wata.[6] A Amurka magani yana biyan kimanin $ 50-100 a kowane wata. A cikin 2017, ita ce magani na 105 da aka fi rubuta a Amurka, tare da fiye da magunguna miliyan bakwai.[7][8]
Bayanan da aka ambata
[gyara sashe | gyara masomin]- 1 2 3 4 5 "Hydralazine Hydrochloride". The American Society of Health-System Pharmacists. Archived from the original on 21 December 2016. Retrieved 8 December 2016.
- 1 2 3 Empty citation (help)
- 1 2 3 (Anthony J. ed.). Missing or empty
|title=(help) - ↑ Empty citation (help)
- ↑ Empty citation (help)
- ↑ "Hydralazine". International Drug Price Indicator Guide. Archived from the original on 22 January 2018. Retrieved 8 December 2016.
- ↑ "The Top 300 of 2020". ClinCalc. Archived from the original on 12 February 2021. Retrieved 11 April 2020.
- ↑ "Hydralazine Hydrochloride - Drug Usage Statistics". ClinCalc. Archived from the original on 8 July 2020. Retrieved 11 April 2020.