Statin

Daga Wikipedia, Insakulofidiya ta kyauta.
Wikidata.svgStatin
drug class (en) Fassara da group or class of molecular entities (en) Fassara
Bayanai
Ƙaramin ɓangare na magani, anticholesteremic agents (en) Fassara, enzyme inhibitor (en) Fassara da oxidoreductase inhibitor (en) Fassara
Bangare na response to statin (en) Fassara
Patientplus ID (en) Fassara lipid-regulating-drugs-including-statins

Statins, wanda kuma aka sani da HMG-CoA reductase inhibitors, wani nau'in magani ne da aka fi amfani da shi don hauhawar cholesterol da cututtukan zuciya.[1] Ana amfani da su duka don hana cututtukan zuciya a cikin waɗanda ke cikin haɗari mai yawa, da kuma waɗanda ke da cututtukan zuciya.[2][3] Ana ɗauke su da baki.[1]

Abubuwan da ake amfani da su sun haɗa da ciwon kai, maƙarƙashiya, da tashin hankali.[4] Mummunan illa na iya haɗawa da raunin tsoka, matsalolin hanta, da ciwon sukari mellitus.[4][5] Ba a ba da shawarar yin amfani da lokacin daukar ciki ko shayarwa ba.[1] Suna hana HMG-CoA reductase enzyme wanda ke rage samar da cholesterol da triglycerides.[1]

An gano Statins a cikin 1971 kuma lovastatin ya shiga aikin likita a cikin 1987.[2][6] Akwai adadin statins a matsayin magani na gama-gari kuma ba su da tsada.[1] Su ne mafi yawan magungunan rage ƙwayar cholesterol.[7] A cikin 2018 atorvastatin shine mafi yawan magunguna a Amurka kuma simvastatin shine na 10 mafi yawan wajabta.[8]

Manazarta[gyara sashe | gyara masomin]

  1. 1.0 1.1 1.2 1.3 1.4 Hitchings, Andrew; Lonsdale, Dagan; Burrage, Daniel; Baker, Emma (2019). The Top 100 Drugs: Clinical Pharmacology and Practical Prescribing (in Turanci) (2nd ed.). Elsevier. p. 204. ISBN 978-0-7020-7442-4.
  2. 2.0 2.1 Template:Cite document
  3. Taylor F, Huffman MD, Macedo AF, Moore TH, Burke M, Davey Smith G, et al. (January 2013). "Statins for the primary prevention of cardiovascular disease". The Cochrane Database of Systematic Reviews. 1 (1): CD004816. doi:10.1002/14651858.CD004816.pub5. PMC 6481400. PMID 23440795.
  4. 4.0 4.1 "List of Statins + Uses, Types & Side Effects". Drugs.com (in Turanci). Retrieved 19 April 2021.
  5. Naci H, Brugts J, Ades T (July 2013). "Comparative tolerability and harms of individual statins: a study-level network meta-analysis of 246 955 participants from 135 randomized, controlled trials" (PDF). Circulation: Cardiovascular Quality and Outcomes. 6 (4): 390–99. doi:10.1161/CIRCOUTCOMES.111.000071. PMID 23838105. S2CID 18340552.
  6. Endo, A (2010). "A historical perspective on the discovery of statins". Proceedings of the Japan Academy. Series B, Physical and biological sciences. 86 (5): 484–93. doi:10.2183/pjab.86.484. PMID 20467214.
  7. "Cholesterol Drugs". American Heart Association. Retrieved 2019-12-24.
  8. "The Top 300 of 2021". clincalc.com. Retrieved 19 April 2021.