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Hypercholesterolemia

Daga Wikipedia, Insakulofidiya ta kyauta.
Hypercholesterolemia
Description (en) Fassara
Iri hyperlipidemia (en) Fassara
Specialty (en) Fassara endocrinology (en) Fassara
Genetic association (en) Fassara CLQTL2 (en) Fassara
Medical treatment (en) Fassara
Magani fluvastatin (en) Fassara
Identifier (en) Fassara
ICD-10 E78.0
ICD-9 272.0
DiseasesDB 6226
MedlinePlus 000403
eMedicine 000403
MeSH D006937

Hypercholesterolemia, wanda kuma ake kira high cholesterol, shine kasancewar yawan matakan cholesterol a cikin jini.[1] Yana da nau'in lipids na jini mara kyau, tare da high triglycerides da low HDL cholesterol.[2][3] Gabaɗaya babu alamun bayyanar.[4] A lokuta masu tsanani xanthomas na iya faruwa.[1] Matsalolin na iya haɗawa da cututtukan zuciya, bugun jini, da cututtukan jijiyoyin jini.[5]

Dalilan na iya haɗawa da cututtukan ƙwayoyin cuta kamar hypercholesterolemia na iyali.[5] Yawancin lokuta; duk da haka, sun kasance saboda haɗuwa da abubuwan da ke tattare da kwayoyin halitta tare da abinci, rashin aiki, kiba da shan taba.[5][4] Sauran abubuwan haɗari sun haɗa da ƙananan thyroid, ciwon nephrotic, cholestasis, barasa, ciwon sukari, da wasu magunguna kamar HCTZ.[5][1] Bincike ya dogara ne akan gwaje-gwajen jini don gano babban adadin cholesterol ko LDL cholesterol.[6][1]

Jiyya yawanci ya ƙunshi canje-canjen salon rayuwa da magunguna.[4] Canje-canjen salon rayuwa sun haɗa da motsa jiki da abinci mai kyau.[1] Idan canje-canjen salon rayuwa bai wadatar ba, ana ba da shawarar magungunan statin sau da yawa.[4] Sauran magungunan da za a iya amfani da su sun haɗa da ezetimibe, niacin, da masu hana PCSK9.[5] Ba kasafai ake yin apheresis na LDL ko dashen hanta ba.[7]

An kiyasta yawan cholesterol yana shafar kusan kashi 39% na mutane a duniya.[8] Kimanin manya miliyan 74 (32%) a Amurka suna da babban cholesterol.[5] Hypercholesterolemia na iyali yana shafar kusan 1 cikin mutane 250.[5] Tsofaffi sun fi shafa.[4] A duk duniya an kiyasta cewa yana haifar da mutuwar mutane kusan miliyan 2.6 a kowace shekara.[8] An fara bayyana hypercholesterolemia na iyali a cikin 1938.[9]

  1. 1.0 1.1 1.2 1.3 1.4 "Quick Facts: High Cholesterol". Merck Manuals Consumer Version. Retrieved 8 March 2021.
  2. Pappan, N; Rehman, A (January 2021). "Dyslipidemia". PMID 32809726. Cite journal requires |journal= (help)
  3. "Hypercholesterolemia - Symptoms, diagnosis and treatment | BMJ Best Practice US". bestpractice.bmj.com. Retrieved 8 March 2021.
  4. 4.0 4.1 4.2 4.3 4.4 "Cholesterol". medlineplus.gov. Retrieved 8 March 2021.
  5. 5.0 5.1 5.2 5.3 5.4 5.5 5.6 Ibrahim, MA; Asuka, E; Jialal, I (January 2021). "Hypercholesterolemia". PMID 29083750. Cite journal requires |journal= (help)
  6. "Hypercholesterolemia - Symptoms, diagnosis and treatment | BMJ Best Practice US". bestpractice.bmj.com. Retrieved 8 March 2021.
  7. Ito MK, McGowan MP, Moriarty PM (June 2011). "Management of familial hypercholesterolemias in adult patients: recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia". J Clin Lipidol. 5 (3 Suppl): S38–45. doi:10.1016/j.jacl.2011.04.001. PMID 21600528.
  8. 8.0 8.1 Noubiap, JJ; Nansseu, JR; Bigna, JJ; Jingi, AM; Kengne, AP (17 March 2015). "Prevalence and incidence of dyslipidaemia among adults in Africa: a systematic review and meta-analysis protocol". BMJ open. 5 (3): e007404. doi:10.1136/bmjopen-2014-007404. PMID 25783427.
  9. Januzzi, James L. (2011). Cardiac Biomarkers in Clinical Practice (in Turanci). Jones & Bartlett Learning. p. 786. ISBN 978-0-7637-6161-5.