Prednisolone
 Prednisolone | |
|---|---|
type of chemical entity (en)  | |
| Bayanai | |
| Ƙaramin ɓangare na | Steroid |
| Amfani | magani |
| Stylized name (en) | prednisoLONE |
| Sinadaran dabara | C₂₁H₂₈O₅ |
| Canonical SMILES (en) | CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O |
| Isomeric SMILES (en) | C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@]34C)O |
| World Health Organisation international non-proprietary name (en) | prednisolone |
| Matsalar da zata iya haifarwa |
depression (en) |
| Ta jiki ma'amala da |
Nuclear receptor subfamily 3 group C member 1 (en) , Nuclear receptor subfamily 3 group C member 2 (en) da Glucocorticoid receptor (en) |
| Pregnancy category (en) |
Australian pregnancy category A (en) da US pregnancy category C (en) |
| Has characteristic (en) |
bitterness (en) |
Prednisolone magani ne na steroid wanda ake amfani dashi don magance wasu allergies, yanayin kumburi, cututtukan autoimmune, da ciwon daji.[1][2] Wasu daga cikin waɗannan yanayi sun haɗa da rashin wadatar adrenocortical, hawan jini na calcium, rheumatoid arthritis, dermatitis, kumburin ido, asma, da kuma sclerosis.[2] Ana amfani da shi ta baki, allura a cikin jijiyoyi, a matsayin cream na fata, da kuma zubar da ido.[2][3][4]
Abubuwan da ke haifar da amfani na ɗan gajeren lokaci sun haɗa da tashin zuciya da jin gajiya.[1] Mafi tsanani illa sun haɗa da matsalolin tabin hankali, wanda zai iya faruwa a cikin kusan 5% na mutane.[5] Illolin gama gari tare da amfani na dogon lokaci sun haɗa da asarar kashi, rauni, cututtukan yisti, da ƙumburi mai sauƙi.[2] Yayin da amfani na ɗan gajeren lokaci a cikin ɓangaren baya na ciki yana da lafiya, amfani na dogon lokaci ko amfani da shi a farkon ciki yana da alaƙa da cutarwa ga jariri.[6] Glucocorticoid ne wanda aka yi daga hydrocortisone (cortisol).[7]
An gano Prednisolone kuma an yarda da shi don amfani da magani a cikin shekarar alif dubu ɗaya da ɗari tara da hamsin da biyar 1955.[7] Yana cikin Jerin Mahimman Magunguna na Hukumar Lafiya ta Duniya.[8] Akwai shi azaman magani na gama-gari. Farashin jimla a cikin ƙasashe masu tasowa kusan dalar Amurka 0.01 akan kowace kwamfutar hannu 5 mg.[9] A cikin shekarar dubu biyu da goma sha’bakwai 2017, shi ne na 129th mafi yawan magunguna a Amurka, tare da magunguna fiye da miliyan biyar.[10][11]
Manazarta
[gyara sashe | gyara masomin]- 1 2 World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. pp. 53–54. hdl:10665/44053. ISBN 9789241547659.
- 1 2 3 4 "Prednisolone". The American Society of Health-System Pharmacists. Archived from the original on 23 December 2016. Retrieved 8 December 2016.
- ↑ "Orapred ODT- prednisolone sodium phosphate tablet, orally disintegrating". DailyMed. 11 September 2019. Retrieved 9 March 2020.
- ↑ "Omnipred- prednisolone acetate suspension". DailyMed. 9 September 2019. Retrieved 9 March 2020.
- ↑ "Pevanti 10mg Tablets – Summary of Product Characteristics (SPC) – (eMC)". www.medicines.org.uk. 1 December 2014. Archived from the original on 20 December 2016. Retrieved 13 December 2016.
- ↑ "Prednisolone Use During Pregnancy". Drugs.com. 16 January 2000. Retrieved 9 March 2020.
- 1 2 Kim, Kyu-Won; Roh, Jae Kyung; Wee, Hee-Jun; Kim, Chan (2016). Cancer Drug Discovery: Science and History. Springer. p. 169. ISBN 9789402408447. Archived from the original on 2017-09-10.
- ↑ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ↑ "Prednisolone" (PDF). WHO International Drug Price Indicator Guide, 2014.
- ↑ "The Top 300 of 2020". ClinCalc. Retrieved 11 April 2020.
- ↑ "Prednisolone - Drug Usage Statistics". ClinCalc. Retrieved 11 April 2020.