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Prednisolone

Daga Wikipedia, Insakulofidiya ta kyauta.
Prednisolone
type of chemical entity (en) Fassara
Bayanai
Ƙaramin ɓangare na steroid (en) Fassara
Amfani magani
Sinadaran dabara C₂₁H₂₈O₅
Canonical SMILES (en) Fassara CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O
Isomeric SMILES (en) Fassara C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@]34C)O
World Health Organisation international non-proprietary name (en) Fassara prednisolone
Matsalar da zata iya haifarwa mental depression (en) Fassara
Ta jiki ma'amala da Nuclear receptor subfamily 3 group C member 1 (en) Fassara, Nuclear receptor subfamily 3 group C member 2 (en) Fassara da Glucocorticoid receptor (en) Fassara
Pregnancy category (en) Fassara Australian pregnancy category A (en) Fassara da US pregnancy category C (en) Fassara
Has characteristic (en) Fassara bitterness (en) Fassara
Stylized name (en) Fassara prednisoLONE

Prednisolone magani ne na steroid wanda ake amfani dashi don magance wasu allergies, yanayin kumburi, cututtukan autoimmune, da ciwon daji.[1][2] Wasu daga cikin waɗannan yanayi sun haɗa da rashin wadatar adrenocortical, hawan jini na calcium, rheumatoid arthritis, dermatitis, kumburin ido, asma, da kuma sclerosis.[2] Ana amfani da shi ta baki, allura a cikin jijiyoyi, a matsayin cream na fata, da kuma zubar da ido.[2][3][4]

Abubuwan da ke haifar da amfani na ɗan gajeren lokaci sun haɗa da tashin zuciya da jin gajiya.[1] Mafi tsanani illa sun haɗa da matsalolin tabin hankali, wanda zai iya faruwa a cikin kusan 5% na mutane.[5] Illolin gama gari tare da amfani na dogon lokaci sun haɗa da asarar kashi, rauni, cututtukan yisti, da ƙumburi mai sauƙi.[2] Yayin da amfani na ɗan gajeren lokaci a cikin ɓangaren baya na ciki yana da lafiya, amfani na dogon lokaci ko amfani da shi a farkon ciki yana da alaƙa da cutarwa ga jariri.[6] Glucocorticoid ne wanda aka yi daga hydrocortisone (cortisol).[7]

An gano Prednisolone kuma an yarda da shi don amfani da magani a cikin 1955.[7] Yana cikin Jerin Mahimman Magunguna na Hukumar Lafiya ta Duniya.[8] Akwai shi azaman magani na gama-gari. Farashin jimla a cikin ƙasashe masu tasowa kusan dalar Amurka 0.01 akan kowace kwamfutar hannu 5 mg.[9] A cikin 2017, shi ne na 129th mafi yawan magunguna a Amurka, tare da magunguna fiye da miliyan biyar.[10][11]

Manazarta

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  1. ↑ 1.0 1.1 World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. pp. 53–54. hdl:10665/44053. ISBN 9789241547659.
  2. ↑ 2.0 2.1 2.2 2.3 "Prednisolone". The American Society of Health-System Pharmacists. Archived from the original on 23 December 2016. Retrieved 8 December 2016.
  3. ↑ "Orapred ODT- prednisolone sodium phosphate tablet, orally disintegrating". DailyMed. 11 September 2019. Retrieved 9 March 2020.
  4. ↑ "Omnipred- prednisolone acetate suspension". DailyMed. 9 September 2019. Retrieved 9 March 2020.
  5. ↑ "Pevanti 10mg Tablets – Summary of Product Characteristics (SPC) – (eMC)". www.medicines.org.uk. 1 December 2014. Archived from the original on 20 December 2016. Retrieved 13 December 2016.
  6. ↑ "Prednisolone Use During Pregnancy". Drugs.com. 16 January 2000. Retrieved 9 March 2020.
  7. ↑ 7.0 7.1 Kim, Kyu-Won; Roh, Jae Kyung; Wee, Hee-Jun; Kim, Chan (2016). Cancer Drug Discovery: Science and History. Springer. p. 169. ISBN 9789402408447. Archived from the original on 2017-09-10.
  8. ↑ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
  9. ↑ "Prednisolone" (PDF). WHO International Drug Price Indicator Guide, 2014.
  10. ↑ "The Top 300 of 2020". ClinCalc. Retrieved 11 April 2020.
  11. ↑ "Prednisolone - Drug Usage Statistics". ClinCalc. Retrieved 11 April 2020.
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