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Ciwon daji na Endometrioid

Daga Wikipedia, Insakulofidiya ta kyauta.
Ciwon daji na Endometrioid
Bayanai
Ƙaramin ɓangare na female reproductive system neoplasm (en) Fassara
NCI Thesaurus ID (en) Fassara C7113

Ciwon daji na Endometrioid wani nau'in ƙari ne wanda ke da kamanni da endometrium /[1] carcinoma na endometrial, kuma sama da kashi uku na lokuta suna da bambancin squamous.

Ciwon daji na Ovarian a cikin mata masu shekaru 20+, tare da yanki mai wakiltar yanayin dangi da launi wakiltar ƙimar rayuwa na shekaru 5 .[2] Ciwon daji na endometrioid ana lakafta shi a ƙasan hagu.

Sun kasance wani ɓangare na saman epithelial tumor rukuni na ovarian neoplasms (10-20% wanda shine nau'in endometrioid). Bambance -bambancen da ba su da kyau da kan iyakoki ba safai ba ne, saboda yawancin suna da muni . Akwai haɗin gwiwa tare da endometriosis da kuma carcinoma na farko na endometrial (ciwon daji na endometrial ).

A kan babban binciken ilimin cututtuka, ƙwayar cuta tana da cystic kuma yana iya zama mai ƙarfi kuma wasu suna tasowa a cikin cystic endometriosis. A cikin kashi 40% na lokuta, ciwace-ciwacen endometrioid ana samun su a gefe guda.[3]

Endometrium

[gyara sashe | gyara masomin]

Ciwon daji na endometrioid kuma na iya tasowa a cikin endometrium.[4][5]

Ana ɗaukar maki 1 da 2 "nau'in 1" ciwon daji na endometrial, yayin da aji 3 ana ɗaukarsa "nau'in 2".[6]

Haske microscope

[gyara sashe | gyara masomin]

Hasken microscopy yana nuna glandan tubular, kama da endometrium.[7]

Halittar kwayoyin halitta

[gyara sashe | gyara masomin]

CTNNB1 da PTEN maye gurbi

[gyara sashe | gyara masomin]

Ovarian da endometrial endometrioid carcinomas suna da CTNNB1 daban-daban da bayanan bayanan maye gurbi na PTEN . Sauye-sauyen PTEN sun fi yawa a cikin ƙananan ƙwayoyin endometrioid carcinomas (67%) idan aka kwatanta da ƙananan ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta (17%). Sabanin haka, maye gurbi na CTNNB1 ya bambanta sosai a cikin ƙananan ƙwayoyin cuta na ovarian endometrioid carcinomas (53%) idan aka kwatanta da ƙananan ƙwayoyin endometrioid carcinomas (28%). Wannan bambance-bambance a cikin mitar maye gurbi na CTNNB1 na iya zama mai nuna alamun ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin cuta; Kwayoyin epithelial da ke rufe wani cyst na endometriotic a cikin ovary an fallasa su zuwa wani yanayi mai oxidative wanda ke inganta ƙwayar cuta.[8]

  1. "Dorlands Medical Dictionary:endometrioid tumor".[permanent dead link]
  2. Kosary, Carol L. (2007). "Chapter 16: Cancers of the Ovary" (PDF). In Baguio, RNL; Young, JL; Keel, GE; Eisner, MP; Lin, YD; Horner, M-J (eds.). SEER Survival Monograph: Cancer Survival Among Adults: US SEER Program, 1988-2001, Patient and Tumor Characteristics. SEER Program. NIH Pub. No. 07-6215. Bethesda, MD: National Cancer Institute. pp. 133–144.
  3. Robbins; Cotran, eds. (2005). Pathologic Basis of Disease (7th ed.). Philadelphia: Saunders. ISBN 978-0-7216-0187-8.
  4. Mulvany NJ, Allen DG (January 2008). "Combined large cell neuroendocrine and endometrioid carcinoma of the endometrium". Int. J. Gynecol. Pathol. 27 (1): 49–57. doi:10.1097/pgp.0b013e31806219c5. PMID 18156975. S2CID 43849133.
  5. Samfuri:MeshName
  6. "ACS :: What Is Endometrial Cancer?". Archived from the original on 2010-06-20. Retrieved 2010-03-24.
  7. Shahrzad Ehdaivand. "Ovary tumor - Endometrioid tumors - General". Pathology Outlines. Archived from the original on 2020-02-16. Retrieved 2020-03-17. Topic Completed: 1 December 2012. Revised: 6 March 2020
  8. McConechy, M. K.; Ding, J; Senz, J; Yang, W; Melnyk, N; Tone, A. A.; Prentice, L. M.; Wiegand, K. C.; McAlpine, J. N.; Shah, S. P.; Lee, C. H.; Goodfellow, P. J.; Gilks, C. B.; Huntsman, D. G. (2014). "Ovarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN mutation profiles". Modern Pathology. 27 (1): 128–34. doi:10.1038/modpathol.2013.107. PMC 3915240. PMID 23765252.