Ciwon daji na Endometrioid
Ciwon daji na Endometrioid | |
---|---|
Bayanai | |
Ƙaramin ɓangare na | female reproductive system neoplasm (en) |
NCI Thesaurus ID (en) | C7113 |
Ciwon daji na Endometrioid wani nau'in ƙari ne wanda ke da kamanni da endometrium /[1] carcinoma na endometrial, kuma sama da kashi uku na lokuta suna da bambancin squamous.
Ovary
[gyara sashe | gyara masomin]Sun kasance wani ɓangare na saman epithelial tumor rukuni na ovarian neoplasms (10-20% wanda shine nau'in endometrioid). Bambance -bambancen da ba su da kyau da kan iyakoki ba safai ba ne, saboda yawancin suna da muni . Akwai haɗin gwiwa tare da endometriosis da kuma carcinoma na farko na endometrial (ciwon daji na endometrial ).
A kan babban binciken ilimin cututtuka, ƙwayar cuta tana da cystic kuma yana iya zama mai ƙarfi kuma wasu suna tasowa a cikin cystic endometriosis. A cikin kashi 40% na lokuta, ciwace-ciwacen endometrioid ana samun su a gefe guda.[3]
Endometrium
[gyara sashe | gyara masomin]Ciwon daji na endometrioid kuma na iya tasowa a cikin endometrium.[4][5]
Ana ɗaukar maki 1 da 2 "nau'in 1" ciwon daji na endometrial, yayin da aji 3 ana ɗaukarsa "nau'in 2".[6]
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Abubuwan da suka shafi ciwon daji na endometrial ta hanyar histopathology, kasancewar endometrioid a yawancin lokuta.
Haske microscope
[gyara sashe | gyara masomin]Hasken microscopy yana nuna glandan tubular, kama da endometrium.[7]
Halittar kwayoyin halitta
[gyara sashe | gyara masomin]CTNNB1 da PTEN maye gurbi
[gyara sashe | gyara masomin]Ovarian da endometrial endometrioid carcinomas suna da CTNNB1 daban-daban da bayanan bayanan maye gurbi na PTEN . Sauye-sauyen PTEN sun fi yawa a cikin ƙananan ƙwayoyin endometrioid carcinomas (67%) idan aka kwatanta da ƙananan ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta (17%). Sabanin haka, maye gurbi na CTNNB1 ya bambanta sosai a cikin ƙananan ƙwayoyin cuta na ovarian endometrioid carcinomas (53%) idan aka kwatanta da ƙananan ƙwayoyin endometrioid carcinomas (28%). Wannan bambance-bambance a cikin mitar maye gurbi na CTNNB1 na iya zama mai nuna alamun ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin cuta; Kwayoyin epithelial da ke rufe wani cyst na endometriotic a cikin ovary an fallasa su zuwa wani yanayi mai oxidative wanda ke inganta ƙwayar cuta.[8]
Manazarta
[gyara sashe | gyara masomin]- ↑ "Dorlands Medical Dictionary:endometrioid tumor".[permanent dead link]
- ↑ Kosary, Carol L. (2007). "Chapter 16: Cancers of the Ovary" (PDF). In Baguio, RNL; Young, JL; Keel, GE; Eisner, MP; Lin, YD; Horner, M-J (eds.). SEER Survival Monograph: Cancer Survival Among Adults: US SEER Program, 1988-2001, Patient and Tumor Characteristics. SEER Program. NIH Pub. No. 07-6215. Bethesda, MD: National Cancer Institute. pp. 133–144.
- ↑ Robbins; Cotran, eds. (2005). Pathologic Basis of Disease (7th ed.). Philadelphia: Saunders. ISBN 978-0-7216-0187-8.
- ↑ Mulvany NJ, Allen DG (January 2008). "Combined large cell neuroendocrine and endometrioid carcinoma of the endometrium". Int. J. Gynecol. Pathol. 27 (1): 49–57. doi:10.1097/pgp.0b013e31806219c5. PMID 18156975. S2CID 43849133.
- ↑ Samfuri:MeshName
- ↑ "ACS :: What Is Endometrial Cancer?". Archived from the original on 2010-06-20. Retrieved 2010-03-24.
- ↑ Shahrzad Ehdaivand. "Ovary tumor - Endometrioid tumors - General". Pathology Outlines. Archived from the original on 2020-02-16. Retrieved 2020-03-17. Topic Completed: 1 December 2012. Revised: 6 March 2020
- ↑ McConechy, M. K.; Ding, J; Senz, J; Yang, W; Melnyk, N; Tone, A. A.; Prentice, L. M.; Wiegand, K. C.; McAlpine, J. N.; Shah, S. P.; Lee, C. H.; Goodfellow, P. J.; Gilks, C. B.; Huntsman, D. G. (2014). "Ovarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN mutation profiles". Modern Pathology. 27 (1): 128–34. doi:10.1038/modpathol.2013.107. PMC 3915240. PMID 23765252.