Maria Mitchell asalin

A cikin 1843,Mitchell ta koma Unitarianism,ko da yake ba ta halarci Cocin Unitarian a jiki ba sai fiye da shekaru ashirin bayan haka.Ficewarta daga bangaskiyar Quaker bai haifar da hutu tare da danginta ba,waɗanda ta bayyana sun kasance kusa da su. Masana tarihi suna da ƙarancin sani game da wannan lokacin a cikin rayuwar Mitchell saboda kaɗan daga cikin takaddun sirrinta sun ragu kafin 1846. Mambobin dangin Mitchell sun yi imanin cewa ta lalata wasu takardun sirrinta da yawa don su kasance masu zaman kansu, saboda sun shaida takardun sirri da babbar wuta ta 1846 ta busa ta hanyar titi, kuma saboda tsoron wata wuta ta ci gaba.