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Coinfection

Daga Wikipedia, Insakulofidiya ta kyauta.
Coinfection
Description (en) Fassara
Iri infection (en) Fassara
secondary infection (en) Fassara
Specialty (en) Fassara infectious diseases (en) Fassara
Identifier (en) Fassara
MeSH D060085

Coinfection shine kamuwa da cuta a lokaci guda na runduna ta nau'ikan kwayoyin cuta masu yawa. A cikin ilimin kwayar cutar virus, tagwayen cuta ya haɗa da kamuwa da rashin lapiya guda daya ta dalilin kwayar cuta guda biyu ko fiye da hakan. Misali shi ne haduwar kwayar cutar hanta B da cutar hanta C a cikin hanta, wanda zai iya tasowa da yawa ta hanyar kamuwa da cuta ta farko.

Ba a san yawan yaduwar wannan yanayin a duniya ba. Ko abin yafaru ne a rashin daidaituwa tsakanin mutane, amma ana tunanin ya zama ruwan dare, [1] wani lokacin ya fi yawa da cuta guda ɗaya. [2] Haɗuwa da helminths yana shafar kusan mutane miliyan 800 a duka fadin duniya. [3]

Coinfection yana da bukatar abashi matukar mahimmancin lafiyar ɗan adam musamman saboda nau'in ƙwayoyin cuta na iya haduwa da juna su cutar da dan adam . Ana tunanin tasirin kwarin gwiwa akan lafiyar ɗan adam mara kyau. [4] Ma'amala na iya yin tasiri mai kyau ko mara kyau akan wasu ƙwayoyin cuta. ingantacciyar hulɗar ƙwayoyin cuta, yana iya haɓakar cututtukGyaraa da kuma ci gabanta, wannan shine ake kira da syndemism . Mu'amala mai cutarwa tsakanin kwayoyin cuta ta haɗa da tsangwama na ƙananan ƙwayoyin cuta lokacin da nau'in ƙwayoyin cuta guda ɗaya ke danne wasu. misali shinePseudomonas aeruginosa (nau'in kwayar cuta) yana kashe ƙwayoyin cuta na Staphylococcus aureus colony .[5] Ba a san cikakken tsarin mu'amular tsakanin nau'ikan kwayoyin cuta ba, oyin cuta ba. har ma a tsakanin waɗanda ke tsakanin cututtukan da ake dauka ta hanyar jima'i. [6] Koyaya, nazarin hanyar samun abinci a ɗan adam yana nuni da cewa akwai yuwuwar yin hulɗa ta hanyar hanyoyin abinci fiye da karyewar garkuwar jiki.[7]

tarin fuka da cutar sida sune cututtukan da sukafi kowane . A wasu ƙasashe, kusan kashi 80% na masu cutar tarin fuka suma suna ɗauke da cutar HIV. [8] An san yuwuwar habaka waɗannan cututtukan guda biyu masu yaduwa da za a danganta su shekaru da yawa.[9]Sauran misalan gama-gari na tsabar kuɗi sune cuta mai karya garkuwar jiki, wanda ya haɗa da haɗakar da kwayar cutar HIV ta ƙarshen zamani tare da ƙwayoyin cuta masu amfani [10]da cututtukan polymicrobial kamar cutar Lyme tare da wasu cututtuka. [11]Haduwar kwayar cuta a lokuta da dama yakan goge alamun ko kuma yawan daya daga cikin kwayoyin cututtuka. misalin hakan shine: rhinovirus da syncytial virus ta numfashi, da kuma metapneumovirus ko parainfluenza cutar.a wadannan kwayoyin cutar suna nuna saka makon awo marar yawa akan wadanda sukeda da wadanda ke da rhinovirus kadai.[12]

Poliovirus

[gyara sashe | gyara masomin]

Poliovirus Kwayar cutar RNA ce wanda tsarin halittar ta yakeda dauri daya. day ce daga cikin dangin Picornaviridae .Haduwa da wasu Kwayoyin cuta da takeyi sun bayyana sannan sun zama gama gari. wadannan hanyoyin sun hada da watsa virions da kuma yada tantanin halittarta. [13] Waɗannan sun haɗa da watsawa ta hanyar tattarawar virion, watsa kwayar cutar kwayar cutar kwayar cutar kwayar cutar kwayar cutar kwayar cuta a cikin vesicles na membrane, da kuma watsuwa wadda bacteria take sakawa.

Drake ya nuna cewa cutar poliovirus tana iya sake dawowa bayan ta warke. da yawa. [14] wannan ze iya faruwa ne lokacin da aka haske cutar ta poliovirus tare da hasken UV. da kuma aka bata damar shiga acikin jiki,cutar polio zata iya samun za a iya samar da zuriya masu yawa na UV koda kuwa yakai yawan wanda yake hana kwayar cutar kara yawa da yaduwa.

Poliovirus na iya fuskantar sake haɗewar kwayoyin halitta da wata virus din lokacin da aƙalla nau'ikan kwayoyin cuta guda biyu suka kasance a cikin tantanin halitta ɗaya. Kirkegaard da Baltimore(mutane masana kimiya) [15] sun gabatar da shaidar cewa RNA polymerase mai dogaro da RNA yana haɓaka haɓakawa ta hanyar zaɓin kwafi wanda RdRP ke canzawa tsakanin (+) samfuran ssRNA yayin haɗakar mara kyau. Sake haɗawa a cikin ƙwayoyin cuta na RNA ya bayyana cewa hanyace ta saka kwayar halittarta wadanda ba lalatattu ba zuwa ga yayanta. [16] [17]

Misali

[gyara sashe | gyara masomin]

Manazarta

[gyara sashe | gyara masomin]
  1. ↑ Cox, FE (2001). "Concomitant infections, parasites and immune responses" (PDF). Parasitology. 122. Suppl: S23–38. doi:10.1017/s003118200001698x. PMID 11442193. S2CID 150432
  2. ↑ Petney, TN; Andrews, RH (1998). "Multiparasite communities in animals and humans: frequency, structure and pathogenic significance". International Journal for Parasitology. 28 (3): 377–93. doi:10.1016/S0020-7519(97)00189-6. PMID 9559357
  3. ↑ Crompton, DW (1999). "How much human helminthiasis is there in the world?". The Journal of Parasitology. 85 (3): 397–403. doi:10.2307/3285768
  4. ↑ Griffiths, EC; Pedersen, ABP; Fenton, A; Petchey, OP (2011). "The nature and consequences of coinfection in humans". Journal of Infection. 63 (3): 200–206. doi:10.1016/j.jinf.2011.06.005
  5. ↑ Hoffman, L. R.; Deziel, E.; D'argenio, D. A.; Lepine, F.; Emerson, J.; McNamara, S.; Gibson, R. L.; Ramsey, B. W.; Miller, S. I. (2006). "Selection for Staphylococcus aureus small-colony variants due to growth in the presence of Pseudomonas aeruginosa". Proceedings of the National Academy of Sciences. 103 (52): 19890–5. Bibcode:2006PNAS..10319890H
  6. ↑ Shrestha, S. (2011). "Influence of host genetic and ecological factors in complex concomitant infections – relevance to sexually transmitted infections". Journal of Reproductive Immunology. 92 (1–2): 27–32. doi:10.1016/j.jri.2011.09.001
  7. ↑ Griffiths, E.; Pedersen, A.; Fenton, A.; Petchey, O. (2014). "Analysis of a summary network of co-infection in humans reveals that parasites interact most via shared resources"
  8. ↑ "Tuberculosis and HIV". World Health Organization. Archived from the original on July 21, 2006.
  9. ↑ Di Perri, G; Cruciani, M; Danzi, MC; Luzzati, R; De Checchi, G; Malena, M; Pizzighella, S; Mazzi, R; et al. (1989). "Nosocomial epidemic of active tuberculosis among HIV-infected patients". Lancet. 2 (8678–8679): 1502–4. doi:10.1016/s0140-6736(89)92942-5. PMID 2574778. S2CID 5608415
  10. ↑ Lawn, SD (2004). "AIDS in Africa: the impact of coinfections on the pathogenesis of HIV-1 infection". Journal of Infection. 48 (1): 1–12. doi:10.1016/j.jinf.2003.09.001. PMID 14667787
  11. ↑ Mitchell, PD; Reed, KD; Hofkes, JM (1996). "Immunoserologic evidence of coinfection with Borrelia burgdorferi, Babesia microti, and human granulocytic Ehrlichia species in residents of Wisconsin and Minnesota". Journal of Clinical Microbiology. 34 (3): 724–7. doi:10.1128/JCM.34.3.724-727.1996. PMC 228878. PMID 8904446
  12. ↑ Waghmare, A; Strelitz, B; Lacombe, K; Perchetti, GA; Nalla, A; Rha, B; Midgley, C; Lively, JY; Klein, EJ; Kuypers, J; Englund, JA (2019). "Rhinovirus in Children Presenting to the Emergency Department: Role of Viral Load in Disease Severity and Co-Infections". Open Forum Infectious Diseases. 6 (10): S915–S916. doi:10.1093/ofid/ofz360.2304. PMC 6810026
  13. ↑ Aguilera ER, Pfeiffer JK. Strength in numbers: Mechanisms of viral co-infection. Virus Res. 2019;265:43-46. doi:10.1016/j.virusres.2019.03.003
  14. ↑ Drake JW (August 1958). "Interference and multiplicity reactivation in polioviruses". Virology. 6 (1): 244–64. doi:10.1016/0042-6822(58)90073-4. PMID 13581529
  15. ↑ Kirkegaard K, Baltimore D (November 1986). "The mechanism of RNA recombination in poliovirus". Cell. 47 (3): 433–43. doi:10.1016/0092-8674(86)90600-8. PMC 7133339. PMID 3021340
  16. ↑ Barr JN, Fearns R (June 2010). "How RNA viruses maintain their genome integrity". The Journal of General Virology. 91 (Pt 6): 1373–87. doi:10.1099/vir.0.020818-0. PMID 20335491
  17. ↑ Bernstein H, Bernstein C, Michod RE (January 2018). "Sex in microbial pathogens". Infection, Genetics and Evolution. 57: 8–25. doi:10.1016/j.meegid.2017.10.024. PMID 29111273
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