Brucellosis

Brucellosis
Description (en)
Iri	primary bacterial infectious disease (en) , bacterial infectious disease (en) , Zoonosis cuta
Specialty (en)	infectious diseases (en) veterinary medicine (en)
Sanadi	Brucella (en) , Brucella melitensis (en) , Brucella abortus (en) , Brucella neotomae (en) , Brucella suis (en) Brucella canis (en)
Symptoms and signs (en)	undulant fever (en) , continuous fever (en) , Rashin karfi, myalgia (en) , anorexia (en) , hepatomegaly (en) , Sifa, arthritis (en) , orchitis (en) , lymphadenopathy (en) neuritis (en)
Physical examination (en)	physical examination (en) , medical history (en) , microbiological culture (en) , complement fixation test (en) , passive hemagglutination test (en) , ELISEA (en) , agglutination test (en) polymerase chain reaction (en)
Medical treatment (en)
Magani	streptomycin (en) , doxycycline (en) , minocycline (en) da rifampicin (en)
Identifier (en)
ICD-10-CM	A23, A23.9, A23.2, A23.0, A23.8, A23.3 da A23.1
ICD-9-CM	023 da 023.9
DiseasesDB	1716
MedlinePlus	000597
eMedicine	000597
MeSH	D002006
Disease Ontology ID	DOID:11077

Brucellosis cuta ce ne da ake samu daga dabbobi, wanda ke faruwa ta hanyar shan madarar da ba a daɗe ba daga dabbobi masu dauke da cuta, ko kusanci da ruwan dake. Hakanan ana kiranta da undulant fever, zazzabin Malta, da zazzabin Mediterranean .

Kwayoyin cutar da ke haifar da wannan cuta, Brucella, ƙananan ƙwayoyin cuta ne, Gram-negative, wadanda basu motsi,basu fidda spore, masu siffiar zagaye ko kuma sanduna. Suna aiki azaman kwayoyin cutar da bazasu iya , rayuwa su kadai ba.kuma suna haifar da cututtuka na yau da kullum, wanda yawanci yana ci gaba har karshen rayuwa. kwayoyin cutar guda hudu sune ke cutar da mutane: B. abortus, B. canis, B. melitensis, da B. suis . B. Abortus ba shi da cutarwa fiye da B. melitensis kuma shi ne da farko cutar ta shanu. B. canis yana shafar karnuka. B. melitensis shine nau'in da ya fi kamuwa da cuta; yakan cutar da awaki da tumaki lokaci-lokaci. B. suis na tsaka-tsakin jijiyoyi ne kuma galibi yana cutar da aladu. Alamomin sun hada da yawan zufa da ciwon gabobi da tsoka . An gane Brucellosis a cikin dabbobi da mutane tun farkon karni na 20.

Alamomin cuta

Alamun sun kasance kamar waɗanda ke da alaƙa da wasu cututtuka masu yawa na zazzaɓi, amma tare da ciwon jiki da gumi na dare. Tsawon lokacin cutar na iya bambanta daga 'yan makonni zuwa watanni masu yawa ko ma shekaru.

A mataki na farko na cutar, zaman kwayar cutar a cikin jini yana faruwa sannan zata iya kaiwa zuwa classic triad na u zazzabin, zufa (sau da yawa tare da wani irin yanayi na wari, da kuma ciwon jiki da kuma kashi. Gwajin jini a zahiri suna nuna ƙarancin garkuwar jiki da yawan jini, suna nuna wasu haɓakar enzymes na hanta kamar aspartate aminotransferase da alanine aminotransferase, kuma suna nuna tabbataccen halayen Bengal rose da Huddleston. Gastrointestinal bayyanar cututtuka faruwa a cikin 70% na lokuta kuma sun hada da tashin zuciya, amai, rage cin abinci, rashin niyya nauyi asara, ciwon ciki, maƙarƙashiya, zawo, an kara girma hanta, hanta kumburi, hanta ƙurji, da kuma kara girman saifa

Abubuwan dake kawo cuta

Brucellosis a cikin mutane yawanci yana hade da shan madara da cuku mai laushi da aka yi daga madarar dabbobi masu dauke da kwayar cutar, da yawa awaki-kamuwa da B. melitensis, kuma tare da bayyanar da sana'a na ma'aikatan dakin gwaje-gwaje, likitocin dabbobi, da ma'aikatan gidan yanka. Wasu allurar rigakafin da ake amfani da su a cikin dabbobi, musamman B. abortus strain 19, kuma suna haifar da cututtuka a cikin mutane idan an yi musu allura da kuskure. Brucellosis yana haifar da zazzaɓi marasa daidaituwa, zubar da ciki, gumi, rauni, anemia, ciwon kai, damuwa, da ciwon tsoka da na jiki. Sauran nau'ikan, B. suis da B. canis, suna haifar da kamuwa da cuta a cikin aladu da karnuka, bi da bi. Binciken gabaɗaya ya goyi bayan cewa brucellosis yana faruwa ne ta dalilin sana'a ga masu kiwon awaki tare da takamaiman wuraren da ke da alaƙa da suka haɗa da raunin wayar da kan jama'a game da yaduwar cututtuka da rashin sanin takamaiman ayyukan gonaki masu aminci kamar ayyukan keɓe .

Bincike

Binciken brucellosis ya dogara ne akan:

Tabbataccen ganewar cutar brucellosis yana buƙatar keɓanta kwayoyin cutar daga jini, ruwan jiki, ko wasu gabban jiki, amma hanyoyin serological na iya zama kawai gwaje-gwaje da ake samu a yawancin wurare.awon daya nuna akwai kwayar cutar na jini yana tsakanin 40 zuwa 70% kuma ba shi da inganci ga B. abortus fiye da B. melitensis ko B. suis .

Ana iya gano takamaiman riga kafin akan ƙwayoyin cuta na lipopolysaccharide da sauran antigens ta daidaitaccen gwajin agglutination ( SAT ), ya tashi Bengal, 2-mercaptoethanol (2-ME), antihuman globulin (Coombs') da kuma kai tsaye enzyme-linked immunosorbent assay ( ELISA ) . SAT shine mafi yawan amfani da serology a cikin wuraren da ke da yawa. Ana ɗaukar titre agglutination mafi girma fiye da 1:160 a cikin wuraren da ba su da alaƙa kuma sama da 1:320 a cikin wuraren da ba su da ƙarfi.